Table 1 Information on the datasets used in this MR analysis
Information | Dataset ID in IEUGWAS | Year | Sample size | Cases | Controls | Sex and gender ratio | Age range | Numbers of SNPs |
|---|---|---|---|---|---|---|---|---|
UC 1 dataset | finn-b-K11_UC_STRICT | 2021 | 218,507 | 2,701 | 215,806 | Males (Proportion NA) and Females (NA) | NA | 16,380,466 |
UC 2 dataset | Ieu-a-32 | 2015 | 27,432 | 6,968 | 20,464 | Males (NA) and Females (NA) | NA | 12,255,197 |
UC 3 dataset | ukb-a-104 | 2017 | 337,159 | 1,795 | 335,364 | Males (NA) and Females (NA) | NA | 10,894,596 |
UC 4 dataset | ukb-d-ULCERNAS | 2018 | 361,194 | 1,903 | 359,291 | Males (NA) and Females (NA) | NA | 10,366,063 |
Heart failure | ebi-a-GCST90018806 | 2021 | 486,160 | 14,262 | 471,898 | Female proportion of UKB recruitments was 53.8%, Finngen 56.3%. | Mean age of UKB recruitments was 56.8 year old, Fin Finngen 51.8-year-old | 24,178,220 |