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Table 1 Characteristics of studies included in systematic review and meta-analyses

From: Health-related quality of life in pediatric patients with intestinal failure without neurodevelopmental delay: a systematic review and meta-analysis

Authors

Year

Design

Sample size

Rater

Age range

Population

Controls

Outcome measures

Country/region

     

Mean (SD)

Median (IQR)

    

Gottrand et al.

2005

multicenter study

72

child

 

4 (NA) years

children receiving HPN

reference pediatric population

Auquei questionnaire, Qualin, Ok.ado, and Subjective

Quality of Life Profile questionnaires

France/ Europe

Kum et al.

2024

cross-sectional

29

child/parent

 

10 (9–13) years

pediatric patients with NEC

age-matched healthy controls

PedsQL™

Hong Kong/Asia

McCaig et al.

2021

cross-sectional

53

child/parent

6.2 (3.9) years

 

patients with PIF

reference pediatric population

PedsQL™

US/NA

Mutanen et al.

2015

cross-sectional

36

child/parent

 

9 (1–27) years

patients with PIF

age-sex-matched healthy controls

PedsQL™

Finland/Europe

Nagelkerke et al.

2022

observational study

35

child/parent

 

5.3 (2.9–9.7) years

children receiving HPN

reference pediatric population

PedsQL™

The

Netherlands/Europe

Neam et al.

2020

cross-sectional

91

child/parent

NA (only < 18 years)

 

patients with PIF

reference pediatric population

PedsQL™

US/NA

Olieman et al.

2012

cross-sectional

31

child/parent

11.8 (4.2) years

 

children with SBS

age-sex-matched healthy controls

PedsQL™

The

Netherlands/Europe

Pederiva et al.

2018

cross-sectional

30

child

10.9 (NA) years

 

children with SBS

reference pediatric population

PedsQL™

UK/Europe

Sanchez et al.

2013

cross-sectional

23

parent

28.54 (16.87) months

 

patients with PIF

reference pediatric population

PedsQL™

US/NA

Silva et al.

2023

retrospective multicenter study

20

child/parent

7.5 (5.0) years

 

patients with PIF/SBS

reference pediatric population

PedsQL™

Portugal/Europe

So et al.

2021

cross-sectional

21

child/parent

 

8.33 (6.96–11.04) years

patients with PIF

age-sex-matched healthy controls

PedsQL™ Physical Function subscale

Canada/NA

Wong et al.

2022

prospective study

69

child/parent

 

8 (6–10) years

patients with PIF

reference pediatric population

PedsQL™

US/NA

  1. Note. HPN = Home parenteral nutrition; SBS = short bowel syndrome; PIF = pediatric intestinal failure; NEC = necrotizing enterocolitis; NA = not available