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Table 4 Gastrointestinal Symptom Rating Scale (GSRS) and Psychological General Well-Being Questionnaire (PGWB) scores for coeliac disease patients (n = 621) with and without recurrent aphthous ulcerations and glossodynia on a gluten-free diet

From: Prevalence of oral manifestations in coeliac disease and associated factors

 

Recurrent aphthous ulcerations

 

Glossodynia

 

Yes, n = 104

No, n = 517

p-value

Yes, n = 85

No, n = 536

p-value

GSRS Total score

2.4 (1.7–2.9)

1.9 (1.5–2.4)

 < 0.001

2.4 (1.8–2.8)

1.9 (1.5–2.5)

 < 0.001

Diarrhoea

1.7 (1.0–2.3)

1.3 (1.0–2.3)

0.262

2.0 (1.0–2.7)

1.3 (1.0–2.3)

0.002

Indigestion

2.9 (2.0–3.8)

2.3 (1.8–3.0)

 < 0.001

3.0 (2.0–3.6)

2.3 (1.8–3.2)

 < 0.001

Constipation

2.0 (1.3–2.7)

1.7 (1.0–2.7)

0.004

2.0 (1.3–2.7)

1.7 (1.0–2.7)

0.006*

Abdominal pain

2.3 (1.7–2.9)

1.7 (1.3–2.3)

 < 0.001

2.3 (1.7–2.7)

1.7 (1.3–2.3)

 < 0.001

Reflux

1.5 (1.0–3.0)

1.5 (1.0–2.0)

0.004

1.5 (1.0–2.5)

1.0 (1.0–2.0)

0.005

PGWB Total score

101 (86–113)

107 (95–115)

0.007

98 (88–111)

107 (96–116)

 < 0.001

Anxiety

24 (19–27)

25 (22–27)

0.018

23 (19–26)

25 (21–27)

0.008

Depressive mood

16 (14–18)

17 (15–18)

0.032

16 (14–18)

17 (15–18)

 < 0.001

Well–being

17 (14–19)

18 (15–20)

0.039*

16 (14–19)

18 (15–20)

0.009

Self–control

15 (13–17)

16 (14–17)

0.009

15 (13–16)

16 (14–17)

0.001

General health

12 (10–15)

13 (11–15)

0.092

12 (9–14)

13 (11–15)

 < 0.001

Vitality

17 (14–20)

18 (16–20)

0.005

17 (15–19)

19 (16–21)

 < 0.001

  1. The values are given as medians with interquartile range
  2. In the GSRS, a higher score indicates more severe symptoms, and in the PGWB, a higher score indicates better quality of life
  3. *Significance disappears after adjusting for gender and age at the time of the study