Fig. 2

Diagnostic ability by the single use of the individual non-invasive markers for endoscopic remission in CD. A The values of each marker were significantly decreased in the group with endoscopic remission. Parallel dotted lines show the cutoff values of the serum/fecal biomarkers in this study: LRG, 13.2 µg/mL; CRP, 0.15 mg/dL; and Fcal, 180 µg/g. B The diagnostic ability of the single use of each marker for endoscopic remission. C The receiver operating characteristic curve for the diagnosis of endoscopic remission by a single use of each marker. LRG, leucine-rich alpha- 2 glycoprotein; CRP, C-reactive protein; Fcal, fecal calprotectin; Sens, sensitivity; Spec, specificity; PPV, positive predictive value; NPV, negative predictive value; AUC, area under the curve; CI, confidence interval