Table 4 Univariate and multivariate Cox regression analyses of overall survival risk factors in 77 HCC patients post - hepatectomy
Characteristic | all | HR (univariable) | HR (multivariable) | |
|---|---|---|---|---|
Treg | Low | 51 (66.2%) | ||
High | 26 (33.8%) | 2.78 (1.27–6.11, p = 0.011) | 4.59 (1.82–11.59, p = 0.001) | |
Sex | female | 14 (18.2%) | ||
male | 63 (81.8%) | 2.86 (0.67–12.13, p = 0.154) | ||
Age | Mean ± SD | 57.9 ± 11.8 | 0.98 (0.95–1.02, p = 0.310) | |
HBV.DNA | < 1000 IU/mL | 49 (63.6%) | ||
> 1000 IU/mL | 28 (36.4%) | 3.28 (1.47–7.32, p = 0.004) | 3.89 (1.36–11.11, p = 0.011) | |
AFP | < 400 ng/mL | 47 (61.0%) | ||
> 400 ng/mL | 30 (39.0%) | 1.54 (0.70–3.38, p = 0.279) | ||
TBIL | Median [Min, Max] | 14.8 [6.50, 141] | 1.01 (1.00-1.03, p = 0.096) | |
ALB | Mean ± SD | 39.0 ± 4.5 | 0.87 (0.79–0.96, p = 0.006) | 0.89 (0.79-1.00, p = 0.058) |
PT | Median [Min, Max] | 11.9 [1.1, 24.9] | 1.03 (0.90–1.18, p = 0.694) | |
Operation. time | Median [Min, Max] | 212 [89.0, 582] | 1.00 (1.00-1.01, p = 0.549) | |
Blood. loss | ≤ 300mL | 60 (77.9%) | ||
¬ 300mL | 17 (22.1%) | 1.37 (0.57–3.28, p = 0.484) | ||
Hepatectomy | ≤ 2 segmentectomy | 63 (81.8%) | ||
> 2 segmentectomy | 14 (18.2%) | 0.47 (0.14–1.59, p = 0.224) | ||
Tumor. diameter | < 5 cm | 37 (48.1%) | ||
> 5 cm | 40 (51.9%) | 2.99 (1.24–7.16, p = 0.014) | 0.98 (0.31–3.15, p = 0.973) | |
Satellite. nodules | No | 59 (76.6%) | ||
Yes | 18 (23.4%) | 2.78 (1.24–6.26, p = 0.013) | 2.45 (0.84–7.14, p = 0.099) | |
MVI | No | 40 (51.9%) | ||
Yes | 37 (48.1%) | 3.00 (1.28–7.01, p = 0.011) | 1.86 (0.69–4.99, p = 0.219) | |
Differentiation | Medium-high | 42 (54.5%) | ||
Low | 35 (45.5%) | 2.02 (0.91–4.49, p = 0.086) | ||