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Table 1 Baseline Characteristics and follow-up data in this study cohort

From: Machine learning for predicting all-cause mortality of metabolic dysfunction-associated fatty liver disease: a longitudinal study based on NHANES

Variables

Total

(n = 3921)

Train set

(n = 3137)

Test set

(n = 784)

P value

Age

48.6 ± 15.07

48.59 ± 15.09

48.68 ± 15.03

0.899

Sex

   

0.250

 Male

1941 (49.50%)

1538 (49.0%)

403 (51.4%)

 

 Female

1980 (50.50%)

1599 (51.0%)

381 (48.6%)

 

Education

   

0.754

 Illiterate

144 (3.70%)

112 (3.57%)

32(4.08%)

 

 Below high school

1019(26.0%)

807 (25.7%)

212 (27.0%)

 

 High school

1848 (47.1%)

1488 (47.4%)

360 (45.9%)

 

 Above high school

910 (23.2%)

730 (23.3%)

180 (23.0%)

 

ethnicity

   

0.586

 non-Hispanic White

2812(71.70%)

2259(72.0%)

553 (70.5%)

 

 non-Hispanic Black

941 (24.00%)

748 (23.8%)

193 (24.6%)

 

 Other

168 (4.30%)

130 (4.14%)

38 (4.85%)

 

Married status

   

0.407

 Married (spouse in household)

2684 (68.50%)

2142 (68.3%)

542 (69.1%)

 

 Married (spouse not in household)

318 (8.10%)

244 (7.78%)

74 (9.44%)

 

 Living as married

333 (8.50%)

274 (8.73%)

59 (7.53%)

 

 Widowed

162 (4.10%)

132 (4.21%)

30 (3.83%)

 

 Divorced

424 (10.80%)

345 (11.0%)

79 (10.1%)

 

Family income–poverty ratio

   

0.640

< 1.3

1470(37.40%)

1172 (37.36%)

298 (38.01%)

 

1.3–3.5

1670(42.59%%)

1347 (42.94%)

323 (41.20%)

 

> 3.5

781(19.91%)

618 (19.70%)

163 (20.79%)

 

BMI

   

0.849

> = 25

3466 (88.40%)

2775 (88.46%)

691 (88.14%)

 

< 25

455 (11.60%)

362 (11.54%)

93 (11.86%)

 

Waist

94.00 [102.00,111.00]

102.00 [94.00,111.90]

101.85 [93.78,111.70]

0.875

Weight

82.80 [72.15,95.80]

82.90[72.10,95.80]

82.35[72.79,95.83]

0.986

Height

166.00 [158.90,173.40]

165.90[158.90,173.40]

166.40[158.30,173.53]

0.732

Hypertension

   

0.387

 Yes

1540 (39.30%)

1221 (38.9%)

319 (40.7%)

 

 No

2381 (60.70%)

1916 (61.1%)

465 (59.3%)

 

Number of cigarettes smoked > 100

   

0.522

 Yes

2048 (52.20%)

1630 (52.0%)

418 (53.3%)

 

 No

1873(47.80%)

1507 (48.0%)

366 (46.7%)

 

Alcohol consumption

1.415[1.201,2.110]

1.415 [1.201,2.110]

1.415[1.201,2.110]

0.568

Diabetes status

   

0.966

 Normal

1104(28.20%)

1300 (41.4%)

321 (40.9%)

 

 Prediabetes

1196(30.50%)

956 (30.5%)

240 (30.6%)

 

 Diabetes

1621 (41.3%)

881 (28.1%)

223 (28.4%)

 

Reported heart disease

   

0.846

 Yes

208 (5.30%)

168 (5.36%)

40 (5.10%)

 

 No

3713(94.70%)

2969 (94.6%)

744 (94.9%)

 

Grade of hepatic steatosis

   

0.594

 Normal/mild

1284(32.75%)

1039 (33.12082%)

245 (31.25000%)

 

 Moderate

1747(44.55%)

1392 (44.37361%)

355 (45.28061%)

 

 Sever

890(22.70%)

706 (22.50558%)

184 (23.46939%)

 

LAP

71.11[44.79,113.16]

71.21[44.88;113.82]

70.59[44.22;109.48]

0.827

ABSI

0.082[0.079,0.085]

0.082 [0.079,0.085]

0.082[0.079,0.085]

0.661

BRI

5.682[4.617,7.075]

5.704[4.628,7.060]

5.622[4.569,7.121]

0.904

CI

0.079[0.075,0.084]

0.079[0.075,0.084]

0.079[0.075,0.084]

0.890

VAI

2.515[1.536,4.173]

2.537[1.543,4.179]

2.450[1.476,4.121]

0.326

FLI

76.49[53.39,91.68]

76.64 [53.27,91.81]

76.15 [53.66,91.44]

0.920

FIB-4

0.874[0.593,1.278]

0.871[0.591,1.269]

0.878[0.598;1.313]

0.521

FORNS

6.29[5.01,6.29]

6.33 [5.07,7.49]

6.28 [5.00,7.36]

0.323

APRI

0.328[0.252,0.441]

0.327[0.252,0.439]

0.334 [0.255,0.449]

0.336

m_APRI

2.323[1.545,3.400]

2.302[1.5384,3.351]

2.393[1.563,3.590]

0.181

AARPRI

0.643[0.472,0.873]

0.639 [0.471;0.873]

0.655 [0.481,0.872]

0.588

AAR

1.17[0.90,1.50]

1.17 [0.91,1.50]

1.17 [0.90,1.47]

0.402

glycosylated hemoglobin (GHb)

5.50[5.10,6.00]

5.50 [5.10,6.00]

5.50 [5.10,6.00]

0.736

Serum triglyceride

1.74[1.19,2.61]

1.75 [1.19,2.61]

1.71 [1.16,2.52]

0.565

Glutamyl transpeptidase (GGT)

29.00[19.00,45.00]

29.00 [19.00,45.00]

29.00 [19.00,46.00]

0.893

Alanine aminotransferase (ALT)

18.00[13.00,27.00]

18.00 [13.00,27.00]

18.00 [13.00,27.00]

0.166

Aspartate transaminase (AST)

21.0[17.00,27.00]

21.00 [17.00,27.00]

21.00 [17.00,27.00]

0.213

High-Density Lipoprotein Cholesterol (HDL-C)

1.14[0.93,1.34]

1.11[0.93,1.34]

1.14[0.96,1.37]

0.370

Platelet counts

271.50[229.50,321.00]

272.00[229.50,322.00]

270.00[228.38,314.63]

0.141

White blood cell

7.20[5.95,9.65]

7.15 [6.00,8.60]

7.20[5.95,8.80]

0.370

Hematocrit

0.422[0.391,0.449]

0.422 [0.391,0.448]

0.422 [0.392,0.451]

0.440

Total Bilirubin

8.55[6.84,11.97]

8.55[6.84,11.97]

8.55[6.84,11.97]

0.345

Total cholesterol

5.46[4.76,6.21]

5.46[4.76,6.21]

5.46 [4.71;6.18]

0.726

Albumin

4.10[3.90,4.30]

4.10 [3.90,4.30]

4.10 [3.90,4.40]

0.975

Time (months)

310[206,336]

310 [207,335]

310 [206,337]

0.881

Death

1815(46.30%)

1452 (46.30%)

363 (46.29%)

1.000

  1. Continuous variables were presented as mean (standard deviation) or median [interquartile range]. Categorical variables were presented as n (%). the P value was calculated by the chi-square test and Wilcoxon rank sum test