Nonlinear association between AST/ALT ratio and 28-day all-cause mortality following ICU admission in critically ill cirrhotic patients: a retrospective cohort study

Table 2 Correlation between aspartate aminotransferase to alanine aminotransferase (AST/ALT) ratio and 28-day mortality following intensive care unit (ICU) admission

Variable	Non-Adjusted OR, 95%CI, p value	Model 1 OR,95%CI, p value	Model 2 OR,95%CI, p value
AST/ALT ratio	1.2 (1.1, 1.3) < 0.001	1.3 (1.2, 1.4) < 0.001	1.1 (1.0, 1.3) 0.002
AST/ALT ratio tertile
T1	Ref	Ref	Ref
T2	1.6 (1.3, 2.1) < 0.001	1.8 (1.4, 2.3) < 0.001	1.6 (1.2, 2.1) 0.003
T3	2.4 (1.9, 3.1) < 0.001	2.8 (2.1, 3.5) < 0.001	2.0 (1.5, 2.7) < 0.001
P for trend	< 0.001	< 0.001	< 0.001

Nonadjusted: Crude model without adjustment
Model 1: Adjusted for age, gender, and ethnicity
Model 2: Adjusted for age, sex, race, hypertension, acute kidney injury, hepatorenal syndrome, ventilation, CRRT, vasoactive agents, diuretics, WBC count, hemoglobin, platelet count, sodium, chloride, SOFA score, and MELD score
Abbreviations: OR odds ratio, CI confidence interval, Ref reference, SOFA Sequential Organ Failure Assessment, MELD Model for End-stage Liver Disease

ISSN: 1471-230X