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Table 4 Association between HbA1c/HDL-C and Moderate-to-advanced fibrosis

From: The HbA1c/HDL-C ratio as a screening indicator of NAFLD in U.S. adults: a cross-sectional NHANES analysis (2017–2020)

 

Model 1

Model 2

Model 3

OR (95%CI)

P

OR (95%CI)

P

OR (95%CI)

P

HbA1c/HDL-C

1.28 (1.23, 1.34)

< 0.001

1.08 (1.02, 1.14)

0.005

1.05 (0.99, 1.11)

0.130

HbA1c/HDL-C quartile

Q1

reference

reference

reference

Q2

1.40 (1.02, 1.92)

0.036

0.87 (0.63, 1.22)

0.428

0.90 (0.64, 1.28)

0.569

Q3

2.51 (1.87, 3.36)

< 0.001

1.08 (0.78, 1.48)

0.655

1.08 (0.77, 1.51)

0.653

Q4

3.99 (3.00, 5.30)

< 0.001

1.13 (0.81, 1.58)

0.463

1.02 (0.71, 1.46)

0.907

  1. Abbreviations: HbA1c/HDL-C ratio: hemoglobin A1c to high-density lipoprotein cholesterol ratio; OR: Odds ratios; CI: confidence interval
  2. Model1 is adjusted for gender, age, race, PIR, education level. Model2 is further adjusted for BMI, smoking, diabetes, Coronary heart disease and hypertension based on Model1. Model3 is additionally adjusted for TG, TC, AST and ALT based on Model2